BDBM250266 US11697636, Example 176::US9452980, 176
SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc(CCC2CCCCN2)cc1
InChI Key InChIKey=MGNGFZXDCWQENS-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 250266
Affinity DataKi: 1nM ΔG°: -12.8kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:The TAAR1 radioligand 3[H]—(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...More data for this Ligand-Target Pair
Affinity DataKi: 25.3nMAssay Description:The TAAR1 radioligand 3[H]—(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...More data for this Ligand-Target Pair
Affinity DataKi: 25.3nM ΔG°: -10.8kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair