BDBM250538 US10167273, Example 17::US10544126, Example 17::US11512066, Example 17::US9475795, 17
SMILES COc1cccc(OC2CCN(CC2)S(=O)(=O)c2c(C)nn(C)c2C)c1
InChI Key InChIKey=XZSMKHKSLZVTOK-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 250538
Affinity DataIC50: 3.60E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:The ability of a compound to block the intracellular release of calcium mediated by PK1 in RBL2H3 cells expressing human PKR1 receptors is determined...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair