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BDBM251680 US9464060, 16

SMILES: OC(=O)c1ccc(CN(CCCc2ccccc2F)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1

InChI Key: InChIKey=YRJOPHXVYGKSJE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251680   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysophosphatidic acid receptor 5 (LPA5)


(Homo sapiens (Human))
BDBM251680
PNG
(US9464060, 16)
Show SMILES OC(=O)c1ccc(CN(CCCc2ccccc2F)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1
Show InChI InChI=1S/C30H25F2NO4/c31-26-8-2-1-6-22(26)7-5-19-33(20-21-11-13-24(14-12-21)30(35)36)29(34)23-15-17-25(18-16-23)37-28-10-4-3-9-27(28)32/h1-4,6,8-18H,5,7,19-20H2,(H,35,36)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...


US Patent US9464060 (2016)


BindingDB Entry DOI: 10.7270/Q23R0RT0
More data for this
Ligand-Target Pair