BDBM251828 US9475779, C.5.1

SMILES CCS(=O)c1cc(ccc1[C@H]1N(C)C(=O)N(C2=C1C(=O)CC2)c1cccc(c1)C(F)(F)F)C#N

InChI Key InChIKey=ABWOANZOKUMITI-PVFJFFHYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251828   

TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM251828(US9475779, C.5.1)
Affinity DataIC50:  1.90nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent