BDBM25192 4-chloro-2-fluoro-5-({7-[2-(hydroxymethyl)-1,3-thiazol-4-yl]quinolin-4-yl}amino)phenol::7-substituted 4-anilinoquinoline, 32

SMILES OCc1nc(cs1)-c1ccc2c(Nc3cc(O)c(F)cc3Cl)ccnc2c1

InChI Key InChIKey=DXSBCUOFFOQDGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25192   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM25192(4-chloro-2-fluoro-5-({7-[2-(hydroxymethyl)-1,3-thi...)
Affinity DataIC50:  25nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compound was determined by incubation with Ret kinase and the substrate in the presence of ATP/ [gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed