BDBM25199 5-{[7-(1-benzofuran-2-yl)quinolin-4-yl]amino}-2-bromophenol::7-substituted 4-anilinoquinoline, 39

SMILES Oc1cc(Nc2ccnc3cc(ccc23)-c2cc3ccccc3o2)ccc1Br

InChI Key InChIKey=SAPRCZLNSVETMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25199   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM25199(5-{[7-(1-benzofuran-2-yl)quinolin-4-yl]amino}-2-br...)
Affinity DataIC50:  85nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compound was determined by incubation with Ret kinase and the substrate in the presence of ATP/ [gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed