BDBM25263 bisphosphonate, 19::{2-[3-(decyloxy)phenyl]-1-hydroxy-1-phosphonoethyl}phosphonic acid

SMILES CCCCCCCCCCOc1cccc(CC(O)(P(O)(O)=O)P(O)(O)=O)c1

InChI Key InChIKey=MHLLAPRPDYGFFU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25263   

TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)
Affinity DataIC50:  590nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed