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BDBM253653 US10179804, Example 132::US9458201, 132

SMILES: CC(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CCCNC(=O)CC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(N)=O

InChI Key: InChIKey=NOFHFWQLYMIMPJ-RZOXKKKKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 253653   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM253653
PNG
(US10179804, Example 132 | US9458201, 132)
Show SMILES CC(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CCCNC(=O)CC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(N)=O
Show InChI InChI=1S/C50H70N16O9/c1-29(67)60-36(15-7-8-20-51)44(70)62-37-16-9-21-56-42(68)19-18-35(43(52)69)61-48(74)40(24-31-26-58-34-14-6-5-13-33(31)34)65-45(71)38(17-10-22-57-50(53)54)63-47(73)39(23-30-11-3-2-4-12-30)64-49(75)41(66-46(37)72)25-32-27-55-28-59-32/h2-6,11-14,26-28,35-41,58H,7-10,15-25,51H2,1H3,(H2,52,69)(H,55,59)(H,56,68)(H,60,67)(H,61,74)(H,62,70)(H,63,73)(H,64,75)(H,65,71)(H,66,72)(H4,53,54,57)/t35-,36-,37-,38-,39+,40-,41-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3n/an/an/an/an/an/an/an/a



Palatin Technologies, Inc.

US Patent


Assay Description
Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...


US Patent US10179804 (2019)

More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM253653
PNG
(US10179804, Example 132 | US9458201, 132)
Show SMILES CC(=O)N[C@@H](CCCCN)C(=O)N[C@H]1CCCNC(=O)CC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O)C(N)=O
Show InChI InChI=1S/C50H70N16O9/c1-29(67)60-36(15-7-8-20-51)44(70)62-37-16-9-21-56-42(68)19-18-35(43(52)69)61-48(74)40(24-31-26-58-34-14-6-5-13-33(31)34)65-45(71)38(17-10-22-57-50(53)54)63-47(73)39(23-30-11-3-2-4-12-30)64-49(75)41(66-46(37)72)25-32-27-55-28-59-32/h2-6,11-14,26-28,35-41,58H,7-10,15-25,51H2,1H3,(H2,52,69)(H,55,59)(H,56,68)(H,60,67)(H,61,74)(H,62,70)(H,63,73)(H,64,75)(H,65,71)(H,66,72)(H4,53,54,57)/t35-,36-,37-,38-,39+,40-,41-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3 -12.1n/an/an/an/an/an/a37



Palatin Technologies, Inc.

US Patent


Assay Description
A competitive inhibition binding assay was performed employing Eu-NDP-α-MSH (PerkinElmer Life Sciences catalog No. AD0225) with determination b...


US Patent US9458201 (2016)


BindingDB Entry DOI: 10.7270/Q2HT2N79
More data for this
Ligand-Target Pair