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BDBM254028 US9493430, 554

SMILES: COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1C)C(O)=O

InChI Key: InChIKey=SUSMOOSYGMJWFW-TXEXFGFSNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254028   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))
BDBM254028
PNG
(US9493430, 554)
Show SMILES COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1C)C(O)=O
Show InChI InChI=1/C36H35F6NO5/c1-19-12-22(32(44)45)6-8-27(19)21-7-9-30(47-5)29(15-21)28-10-11-34(3,4)17-24(28)18-43-20(2)31(48-33(43)46)23-13-25(35(37,38)39)16-26(14-23)36(40,41)42/h6-9,12-16,20,31H,10-11,17-18H2,1-5H3,(H,44,45)/t20-,31-/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.80n/an/an/an/an/an/a



Chong Kun Dang Pharmaceutical Corp.

US Patent


Assay Description
As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...


Citation and Details
More data for this
Ligand-Target Pair