BDBM25447 4-[6-(4-methoxyphenyl)-1H-inden-3-yl]pyridine::Abiraterone mimetic, 10

SMILES COc1ccc(cc1)-c1ccc2C(=CCc2c1)c1ccncc1

InChI Key InChIKey=YEHPQYGKQIAHAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25447   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25447(4-[6-(4-methoxyphenyl)-1H-inden-3-yl]pyridine | Ab...)
Affinity DataIC50:  2.39E+3nMAssay Description:To measure CYP3A4 activity, the product of testosterone 6-hydroxylation, 6beta-hydroxytestosterone was determined. After incubation, the reaction was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25447(4-[6-(4-methoxyphenyl)-1H-inden-3-yl]pyridine | Ab...)
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed