BDBM254502 US9468661, 80::US9468661, 82

SMILES CC1[C@@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccncc23)C1(Cl)Cl

InChI Key InChIKey=GZCVDKPVTVOYQX-GNTFLVLBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 254502   

TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM254502(US9468661, 80 | US9468661, 82)
Affinity DataIC50:  85nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM254502(US9468661, 80 | US9468661, 82)
Affinity DataIC50:  98nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent