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BDBM25467 2,4-dinitro-9H-fluoren-9-one::NSC55545

SMILES: [O-][N+](=O)c1cc2C(=O)c3ccccc3-c2c(c1)[N+]([O-])=O

InChI Key: InChIKey=HUNDKIPOXXHMOS-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25467   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine Phosphosulfate Reductase (APSR)


(Mycobacterium tuberculosis)
BDBM25467
PNG
(2,4-dinitro-9H-fluoren-9-one | NSC55545)
Show SMILES [O-][N+](=O)c1cc2C(=O)c3ccccc3-c2c(c1)[N+]([O-])=O
Show InChI InChI=1S/C13H6N2O5/c16-13-9-4-2-1-3-8(9)12-10(13)5-7(14(17)18)6-11(12)15(19)20/h1-6H
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/a 4.81E+4n/an/an/a7.530



The Scripps Research Institute



Assay Description
Values of Ki were determined from the dependence of the observed rate constant (kobs) on inhibitor concentration. With subsaturing APS, the inhibit...


J Med Chem 51: 6627-30 (2008)


Article DOI: 10.1021/jm800571m
BindingDB Entry DOI: 10.7270/Q2PK0DFG
More data for this
Ligand-Target Pair