BDBM254987 US9475813, 43
SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)N1CN(C2CC2)C(=O)c2cnc3[nH]ccc3c12
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 254987
Affinity DataIC50: 1.80nMAssay Description:The inhibitory activity of the compounds of the present invention against JAK was measured.The respective enzymes (JAK1, JAK2, JAK3 and Tyk2) were pu...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nissan Chemical Industries
US Patent
Nissan Chemical Industries
US Patent
Affinity DataIC50: 91nMAssay Description:The inhibitory activity of the compounds of the present invention against JAK was measured.The respective enzymes (JAK1, JAK2, JAK3 and Tyk2) were pu...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:The inhibitory activity of the compounds of the present invention against JAK was measured.The respective enzymes (JAK1, JAK2, JAK3 and Tyk2) were pu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:The inhibitory activity of the compounds of the present invention against JAK was measured.The respective enzymes (JAK1, JAK2, JAK3 and Tyk2) were pu...More data for this Ligand-Target Pair