BDBM255402 US9481682, 153

SMILES Nc1ncc(Cl)n2c(nc(-c3ccc(cc3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@@H]1CC[C@H]2CCC(=O)N2C1

InChI Key InChIKey=RSVROMVDYUXPKV-AEFFLSMTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255402   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM255402(US9481682, 153)
Affinity DataIC50:  0.160nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent