BDBM255494 US9499493, R940275

SMILES CC(C)(C)C(=O)Nc1cccc(Nc2ncc(F)c(Nc3cccc(O)c3)n2)c1

InChI Key InChIKey=RJPKZOLIFZKLTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255494   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM255494(US9499493, R940275)
Affinity DataIC50:  734nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent