BDBM255513 US10828301, Compound R940338::US9499493, R940338

SMILES Cn1ncc2cc(Nc3ncc(F)c(Nc4ccc5OC(C)(C)C(=O)Nc5c4)n3)ccc12

InChI Key InChIKey=YJZNNCBZUHWOEH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255513   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255513(US10828301, Compound R940338 | US9499493, R940338)
Affinity DataIC50:  28nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255513(US10828301, Compound R940338 | US9499493, R940338)
Affinity DataIC50:  28nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent