BDBM25570 2,6-Disubstituted Pyrazine, 13::4-{6-[(3,4,5-trimethoxyphenyl)amino]pyrazin-2-yl}benzamide
SMILES COc1cc(Nc2cncc(n2)-c2ccc(cc2)C(N)=O)cc(OC)c1OC
InChI Key InChIKey=LZLKDDDQYGMZTB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 25570
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Cancer Research Uk Centre For Cancer Therapeutics
Cancer Research Uk Centre For Cancer Therapeutics
Affinity DataIC50: 1.10E+3nMpH: 7.2 T: 22°CAssay Description:BRAF kinase activity was quantified using a DELFIA-based MEK1 phosphorylation assay. IC50 values were derived from the sigmoidal dose-response curves...More data for this Ligand-Target Pair