BDBM256137 US9487462, 19

SMILES CCOC(=O)c1csc(CN(Cc2ccc(OCc3ccncc3)cc2)Cc2cccnc2)n1

InChI Key InChIKey=OMSFKRAXXCGVKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 256137   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmahungary 2000

US Patent
LigandPNGBDBM256137(US9487462, 19)
Affinity DataIC50:  2.00E+5nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmahungary 2000

US Patent
LigandPNGBDBM256137(US9487462, 19)
Affinity DataIC50:  1.90E+5nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCollagenase 3(Homo sapiens (Human))
Pharmahungary 2000

US Patent
LigandPNGBDBM256137(US9487462, 19)
Affinity DataIC50:  1.90E+4nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmahungary 2000

US Patent
LigandPNGBDBM256137(US9487462, 19)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent