BDBM25654 5-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-2,3-dihydro-1H-isoindol-1-one::pyrazole based inhibitor, 36

SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc2C(=O)NCc2c1

InChI Key InChIKey=FLQRRMNRUINMJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25654   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM25654(5-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-2,3-...)
Affinity DataIC50:  94nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM25654(5-[1-methyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl]-2,3-...)
Affinity DataIC50:  68.4nMAssay Description:Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed