BDBM256716 US9487511, 101

SMILES OC(=O)c1ccc(CN2CCC(CN[C@@H]3C[C@@H]3c3cc(cs3)C(=O)NC3CCC(F)(F)CC3)CC2)cc1

InChI Key InChIKey=DKGRZQXQDYBUCJ-BJKOFHAPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 256716   

TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833](Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256716(US9487511, 101)
Affinity DataIC50: <100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256716(US9487511, 101)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK. A test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256716(US9487511, 101)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent