BDBM25807 4,4 -Dihydroxybenzophenone::4-[(4-hydroxyphenyl)carbonyl]phenol::Bis(p-hydroxy)benzophenone::Compound 0627-0373 (DHBP)::US9688816, N

SMILES Oc1ccc(cc1)C(=O)c1ccc(O)cc1

InChI Key InChIKey=RXNYJUSEXLAVNQ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 25807   

TargetLanosterol 14-alpha demethylase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University Of California San Francisco

LigandPNGBDBM25807(4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...)
Affinity DataKd:  2.80E+4nMpH: 7.5 T: 2°CAssay Description:The assay was developed based on the optical spectral property of P450 enzyme to elicit both type I and type II spectral changes (350 nm through 450 ...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM25807(4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...)
Affinity DataIC50:  3.20E+4nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM25807(4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...)
Affinity DataIC50:  3.10E+4nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM25807(4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)c...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed