BDBM258330 US9493485, 11-173

SMILES C[C@]1(CC2(CCC2)OC(N)=N1)c1cc(Nc2ncnc3cc(Cl)ccc23)ccc1F

InChI Key InChIKey=YQTDBQHMEOODEP-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258330   

TargetBeta-secretase 1(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM258330(US9493485, 11-173)
Affinity DataIC50:  8.55E+3nMpH: 4.5 T: 2°CAssay Description:Compounds are also assessed for BACE1 and Cathepsin D activity using an FP Assay. Compounds to be assessed (e.g. compounds as described in the above ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent