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BDBM258747 US9499482, 146

SMILES: COc1cc(ccc1OCCN1CC[C@@H](F)C1)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O

InChI Key: InChIKey=MHMJMMVEKXJVCO-HXUWFJFHSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258747   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)


(Homo sapiens (Human))
BDBM258747
PNG
(US9499482, 146)
Show SMILES COc1cc(ccc1OCCN1CC[C@@H](F)C1)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O
Show InChI InChI=1S/C26H29FN2O4/c1-31-25-16-21(6-9-23(25)32-15-14-28-12-10-20(27)17-28)29-13-11-24(26(29)30)33-22-7-4-19(5-8-22)18-2-3-18/h4-9,11,16,18,20H,2-3,10,12-15,17H2,1H3/t20-/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
0.600n/an/an/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...


US Patent US9499482 (2016)


BindingDB Entry DOI: 10.7270/Q2M907KT
More data for this
Ligand-Target Pair