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BDBM258751 US9499482, 150

SMILES: COc1cc(ccc1OCCN1CCC[C@@H]1CO)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O

InChI Key: InChIKey=OFLSNCZGSYCOOF-JOCHJYFZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258751   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)


(Homo sapiens (Human))
BDBM258751
PNG
(US9499482, 150)
Show SMILES COc1cc(ccc1OCCN1CCC[C@@H]1CO)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O
Show InChI InChI=1S/C27H32N2O5/c1-32-26-17-21(8-11-24(26)33-16-15-28-13-2-3-22(28)18-30)29-14-12-25(27(29)31)34-23-9-6-20(7-10-23)19-4-5-19/h6-12,17,19,22,30H,2-5,13-16,18H2,1H3/t22-/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.700n/an/an/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...


US Patent US9499482 (2016)


BindingDB Entry DOI: 10.7270/Q2M907KT
More data for this
Ligand-Target Pair