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BDBM258756 US9499482, 155

SMILES: COC1CN(CCOc2ccc(cc2OC)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1

InChI Key: InChIKey=VEQHVRMDPRCUAI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258756   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)


(Homo sapiens (Human))
BDBM258756
PNG
(US9499482, 155)
Show SMILES COC1CN(CCOc2ccc(cc2OC)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1
Show InChI InChI=1S/C26H30N2O5/c1-30-22-16-27(17-22)13-14-32-23-10-7-20(15-25(23)31-2)28-12-11-24(26(28)29)33-21-8-5-19(6-9-21)18-3-4-18/h5-11,15,18,22H,3-4,12-14,16-17H2,1-2H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.5n/an/an/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...


US Patent US9499482 (2016)


BindingDB Entry DOI: 10.7270/Q2M907KT
More data for this
Ligand-Target Pair