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BDBM258762 US9499482, 161

SMILES: COc1cc(ccc1OCCN1CC(C)(C1)OC)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O

InChI Key: InChIKey=ZHTRFFDXJZUYSA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258762   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)


(Homo sapiens (Human))
BDBM258762
PNG
(US9499482, 161)
Show SMILES COc1cc(ccc1OCCN1CC(C)(C1)OC)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O
Show InChI InChI=1S/C27H32N2O5/c1-27(32-3)17-28(18-27)14-15-33-23-11-8-21(16-25(23)31-2)29-13-12-24(26(29)30)34-22-9-6-20(7-10-22)19-4-5-19/h6-12,16,19H,4-5,13-15,17-18H2,1-3H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
0.5n/an/an/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...


US Patent US9499482 (2016)


BindingDB Entry DOI: 10.7270/Q2M907KT
More data for this
Ligand-Target Pair