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BDBM258763 US9499482, 163

SMILES: COc1cc(ccc1OCCN1CC(C1)NC(=O)OC(C)(C)C)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O

InChI Key: InChIKey=IMRFKYXTCFHUPR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258763   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)


(Homo sapiens (Human))
BDBM258763
PNG
(US9499482, 163)
Show SMILES COc1cc(ccc1OCCN1CC(C1)NC(=O)OC(C)(C)C)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O
Show InChI InChI=1S/C30H37N3O6/c1-30(2,3)39-29(35)31-22-18-32(19-22)15-16-37-25-12-9-23(17-27(25)36-4)33-14-13-26(28(33)34)38-24-10-7-21(8-11-24)20-5-6-20/h7-13,17,20,22H,5-6,14-16,18-19H2,1-4H3,(H,31,35)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
0.400n/an/an/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...


US Patent US9499482 (2016)


BindingDB Entry DOI: 10.7270/Q2M907KT
More data for this
Ligand-Target Pair