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BDBM258795 US9499482, 214

SMILES: COc1cc(ccc1OCCN1CCC[C@H]1CO)N1CC=C(Oc2ccc(cc2)-c2ccccc2)C1=O

InChI Key: InChIKey=VVIDGBFJLINKCE-VWLOTQADSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258795   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T)


(Homo sapiens (Human))
BDBM258795
PNG
(US9499482, 214)
Show SMILES COc1cc(ccc1OCCN1CCC[C@H]1CO)N1CC=C(Oc2ccc(cc2)-c2ccccc2)C1=O
Show InChI InChI=1S/C30H32N2O5/c1-35-29-20-24(11-14-27(29)36-19-18-31-16-5-8-25(31)21-33)32-17-15-28(30(32)34)37-26-12-9-23(10-13-26)22-6-3-2-4-7-22/h2-4,6-7,9-15,20,25,33H,5,8,16-19,21H2,1H3/t25-/m0/s1
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PC cid
PC sid
UniChem
US Patent
0.400n/an/an/an/an/an/a7.4n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...


US Patent US9499482 (2016)


BindingDB Entry DOI: 10.7270/Q2M907KT
More data for this
Ligand-Target Pair