BDBM25898 7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide::Chinethazonum::Quinethazone

SMILES CCC1NC(=O)c2cc(c(Cl)cc2N1)S(N)(=O)=O

InChI Key InChIKey=AGMMTXLNIQSRCG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25898   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM25898(7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoli...)
Affinity DataKi:  1.26E+3nM ΔG°:  -8.04kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM25898(7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoli...)
Affinity DataKi:  3.50E+4nM ΔG°:  -6.07kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank