BDBM25914 3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide::BMC173212 Compound 2j::indole sulfonamide, 8j

SMILES NNC(=O)c1[nH]c2ccc(cc2c1-c1ccccc1Br)S(N)(=O)=O

InChI Key InChIKey=XQBLSLMDDOHBFU-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 25914   

TargetCarbonic anhydrase 14(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  9.30nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  48.5nM ΔG°:  -9.97kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  74nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  77nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  81nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  83nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  110nM ΔG°:  -9.49kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-carbonic anhydrase domain-containing protein(Caenorhabditis elegans)
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  260nM ΔG°:  -8.98kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  842nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  947nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  992nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  6.95E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  7.33E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25914(3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-...)
Affinity DataKi:  3.90E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed