BDBM259360 US9505745, 37::US9790212, Example 37

SMILES Cc1c(csc1C(O)[C@H]1CC[C@H](N)CC1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259360   

LigandPNGBDBM259360(US9505745, 37 | US9790212, Example 37)
Affinity DataIC50:  501nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM259360(US9505745, 37 | US9790212, Example 37)
Affinity DataIC50:  501nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent