BDBM259819 US9505766, 20
SMILES CS(=O)(=O)C(=C\c1ccc(cc1)-c1ncnc2[nH]cnc12)\C#N
InChI Key InChIKey=NUTCBXHBYDJNKL-WUXMJOGZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 259819
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 6.00E+4nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2 [C22A](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: >1.00E+4nMpH: 7.6 T: 2°CAssay Description:For RSK2 kinase assays, see Example 64 above. Full-length human T175A NEK2 (referred to as NEK2) was expressed and purified as previously described (...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek2 [T175A](Homo sapiens (Human))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 200nMpH: 7.6 T: 2°CAssay Description:For RSK2 kinase assays, see Example 64 above. Full-length human T175A NEK2 (referred to as NEK2) was expressed and purified as previously described (...More data for this Ligand-Target Pair