BDBM259824 US9505766, 25
SMILES O=C(N1CCCC1)C(=C\c1ccc2cn[nH]c2c1)\C#N
InChI Key InChIKey=YZHVOWFHVJPKPH-NTUHNPAUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259824
TargetSerine/threonine-protein kinase Nek2 [T175A](Homo sapiens (Human))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataIC50: 6.50E+3nMpH: 7.6 T: 2°CAssay Description:For RSK2 kinase assays, see Example 64 above. Full-length human T175A NEK2 (referred to as NEK2) was expressed and purified as previously described (...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataIC50: 2.60E+3nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair