BDBM260152 US9522910, Table 1 Compound 2: 3-[2-(1H-1,3-benzodiazol-1-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cn3cnc4ccccc34)cc2C(F)(F)F)CC1

InChI Key InChIKey=PZALELDRQXQLPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260152   

TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260152(US9522910, Table 1 Compound 2: 3-[2-(1H-1,3-benzod...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Obshchestvo S Ogranichennoy Otvetstvennostyou “Fusion Pharma”

US Patent
LigandPNGBDBM260152(US9522910, Table 1 Compound 2: 3-[2-(1H-1,3-benzod...)
Affinity DataIC50: <20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent