BDBM26033 4-({2-[(4-bromophenyl)(ethyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide::arylaminobenzimidazole, 28

SMILES CCn1c(Nc2ccc(Br)cc2)nc2cc(Oc3ccnc(c3)C(=O)NC)ccc12

InChI Key InChIKey=OCRUKNPFPIICEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26033   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Novartis

LigandPNGBDBM26033(4-({2-[(4-bromophenyl)(ethyl)amino]-1H-1,3-benzodi...)
Affinity DataIC50:  68nMAssay Description:To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

LigandPNGBDBM26033(4-({2-[(4-bromophenyl)(ethyl)amino]-1H-1,3-benzodi...)
Affinity DataIC50:  18nMpH: 7.8 T: 2°CAssay Description:To measure compound inhibitor effects on the ability of Raf enzymes to phosphorylate the Mek substrate, a capture ELISA utilizing streptavidin-coated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed