BDBM260533 US10300066, Compound 7::US9532990, 7

SMILES C\C(O)=C(\C#N)C(=O)N1CCCC(C1)n1nc(-c2ccc(cc2F)C(=O)c2cccc(F)c2)c2c(N)ncnc12

InChI Key InChIKey=XEYOPSLNAJLQJO-RCCKNPSSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260533   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260533(US10300066, Compound 7 | US9532990, 7)
Affinity DataIC50:  730nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260533(US10300066, Compound 7 | US9532990, 7)
Affinity DataIC50:  730nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent