BDBM260538 US10300066, Compound 12::US9532990, 12

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4cccc(F)c4[N+]([O-])=O)cc3F)c12)C1CCCN(C1)C(=O)C=C

InChI Key InChIKey=HPTHOKBXRSRFBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260538   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260538(US10300066, Compound 12 | US9532990, 12)
Affinity DataIC50:  2nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260538(US10300066, Compound 12 | US9532990, 12)
Affinity DataIC50:  2nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent