BDBM260621 US10300066, Compound 95::US9532990, 95

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4ncccn4)cc3F)c12)[C@@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=AWMHCJOHTQSFEM-CYBMUJFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260621   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260621(US10300066, Compound 95 | US9532990, 95)
Affinity DataIC50:  5nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260621(US10300066, Compound 95 | US9532990, 95)
Affinity DataIC50:  5nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent