BDBM26067 3-(4-fluorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 13::WAY-214950

SMILES Fc1ccc(cc1)-c1n(Cc2ccccc2F)nc2c(cccc12)C(F)(F)F

InChI Key InChIKey=NHSFDMDEDPAKNH-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26067   

TargetOxysterols receptor LXR-alpha [197-447](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM26067(3-(4-fluorophenyl)-2-[(2-fluorophenyl)methyl]-7-(t...)
Affinity DataIC50:  248nM EC50:  6.10E+3nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM26067(3-(4-fluorophenyl)-2-[(2-fluorophenyl)methyl]-7-(t...)
Affinity DataIC50:  33nM EC50:  4.15E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed