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BDBM261392 US9708253, 50

SMILES: Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)NC(=O)CC#N)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=SHUMURFWTMNLMY-RVWIWJKTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261392   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM261392
PNG
(US9708253, 50)
Show SMILES Fc1ccc(cc1)S(=O)(=O)[C@@]1(CC[C@@H](CC1)NC(=O)CC#N)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C24H20F8N2O3S/c25-17-5-7-19(8-6-17)38(36,37)21(12-9-18(10-13-21)34-20(35)11-14-33)15-1-3-16(4-2-15)22(26,23(27,28)29)24(30,31)32/h1-8,18H,9-13H2,(H,34,35)/t18-,21+
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 80n/an/an/an/an/a25



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...


US Patent US9708253 (2017)

More data for this
Ligand-Target Pair