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BDBM261409 US9708253, 67

SMILES: Fc1ccc(cc1)S(=O)(=O)C1(CCc2nn(Cc3ccncc3)cc2C1)c1ccc(cc1)C(OCc1c(F)cccc1F)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=NIOSVXHDARTSHR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261409   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM261409
PNG
(US9708253, 67)
Show SMILES Fc1ccc(cc1)S(=O)(=O)C1(CCc2nn(Cc3ccncc3)cc2C1)c1ccc(cc1)C(OCc1c(F)cccc1F)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C35H26F9N3O3S/c36-26-8-10-27(11-9-26)51(48,49)32(15-12-31-23(18-32)20-47(46-31)19-22-13-16-45-17-14-22)24-4-6-25(7-5-24)33(34(39,40)41,35(42,43)44)50-21-28-29(37)2-1-3-30(28)38/h1-11,13-14,16-17,20H,12,15,18-19,21H2
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 93n/an/an/an/an/a25



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...


US Patent US9708253 (2017)

More data for this
Ligand-Target Pair