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BDBM261442 US9708253, 101

SMILES: OC(c1ccc(cc1)[C@@]1(CC[C@@H](CC1)NC(=O)Cc1ccncc1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=JDSRILRTMHCPMR-RZFKFIIISA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261442   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM261442
PNG
(US9708253, 101)
Show SMILES OC(c1ccc(cc1)[C@@]1(CC[C@@H](CC1)NC(=O)Cc1ccncc1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C28H25F7N2O4S/c29-21-5-7-23(8-6-21)42(40,41)25(13-9-22(10-14-25)37-24(38)17-18-11-15-36-16-12-18)19-1-3-20(4-2-19)26(39,27(30,31)32)28(33,34)35/h1-8,11-12,15-16,22,39H,9-10,13-14,17H2,(H,37,38)/t22-,25-
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.73E+3n/an/an/an/an/a25



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...


US Patent US9708253 (2017)

More data for this
Ligand-Target Pair