BDBM261486 US10011568, Ex. No. 9::US9708266, 9

SMILES CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnc(cc1-c1ccccc1C)C1CCC(CC(O)=O)CC1

InChI Key InChIKey=FLJIWCZSOWTRAR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261486   

TargetSubstance-P receptor(Homo sapiens (Human))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261486(US10011568, Ex. No. 9 | US9708266, 9)
Affinity DataIC50:  2.35nMpH: 7.4 T: 2°CAssay Description:The buffer solution for the receptor binding test was dispensed to the wells of a 96-well assay plate (Greiner) at 22.5 μL/well. DMSO solutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261486(US10011568, Ex. No. 9 | US9708266, 9)
Affinity DataIC50:  6.90E+3nMAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSubstance-P receptor(Homo sapiens (Human))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261486(US10011568, Ex. No. 9 | US9708266, 9)
Affinity DataIC50:  2.35nMAssay Description:The buffer solution for the receptor binding test was dispensed to the wells of a 96-well assay plate (Greiner) at 22.5 μL/well. DMSO solutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261486(US10011568, Ex. No. 9 | US9708266, 9)
Affinity DataIC50:  6.90E+3nMpH: 7.4 T: 2°CAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent