BDBM261543 US10513499, Compound 9::US11254644, Compound 9::US9708272, 9

SMILES CCOC(=O)c1cccc(CSc2nc(-c3ccc(C)cc3)c(C#N)c(=O)[nH]2)c1

InChI Key InChIKey=MPBOXDWGHYBOFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 261543   

Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

US Patent
LigandPNGBDBM261543(US10513499, Compound 9 | US11254644, Compound 9 | ...)
Affinity DataIC50:  960nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (3OH-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

US Patent
LigandPNGBDBM261543(US10513499, Compound 9 | US11254644, Compound 9 | ...)
Affinity DataIC50:  960nMAssay Description:The activity of compounds 1-19 and 21-23 as inhibitors of ACMSD1 was determined by measuring the conversion of 3OH-Anthranilic Acid into product (i.e...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

US Patent
LigandPNGBDBM261543(US10513499, Compound 9 | US11254644, Compound 9 | ...)
Affinity DataIC50:  960nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (30H-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In DepthDetails US Patent