BDBM261614 S)-4-(1,5-diphenyl-1H-pyrazol-3-yl)-1-(2,2-diphenylacetyl)-piperazine-2-carboxylic acid::US9708275, Compound 6

SMILES OC(=O)[C@@H]1CN(CCN1C(=O)C(c1ccccc1)c1ccccc1)c1cc(-c2ccccc2)n(n1)-c1ccccc1

InChI Key InChIKey=MHKPIRJTCJZHFN-PMERELPUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261614   

TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM261614(S)-4-(1,5-diphenyl-1H-pyrazol-3-yl)-1-(2,2-dipheny...)
Affinity DataIC50:  3.05E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent