BDBM261624 4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-(phenylethynyl)phenyl)thiazol-2-yl)benzamide::US9708279, 1

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2nc(cs2)-c2cccc(c2)C#Cc2ccccc2)CC1

InChI Key InChIKey=YNUNEXVYXOJLQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261624   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261624(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-(phenyl...)
Affinity DataIC50:  5.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261624(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-(phenyl...)
Affinity DataIC50:  7.10E+4nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent