BDBM261732 1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahydro- 2H-pyran-4-yl)-4- ((6-(1-methyl-1H- pyrazol-4-yl)pyridin- 3-yl)methyl)-2- naphthamide::US9708302, 18::US9708302, 20

SMILES Cn1cc(cn1)-c1ccc(Cc2cc(C(=O)N[C@H]3CCOC[C@@H]3O)c(F)c3ccccc23)cn1

InChI Key InChIKey=PQZBCCGOIMNBLV-ZEQRLZLVSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261732   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM261732(1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahydro- 2H-py...)
Affinity DataEC50:  3nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(RAT)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261732(1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahydro- 2H-py...)
Affinity DataEC50:  2nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(RAT)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261732(1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahydro- 2H-py...)
Affinity DataEC50:  6nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM261732(1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahydro- 2H-py...)
Affinity DataEC50:  2nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent