BDBM261876 2-[9-(Cyclobutylmethyl)-9H-carbazol-3-yl]-1-(cyclopropylmethyl)-1H-benzimidazole-5-carboxylic acid::US9708311, 125

SMILES OC(=O)c1ccc2n(CC3CC3)c(nc2c1)-c1ccc2n(CC3CCC3)c3ccccc3c2c1

InChI Key InChIKey=URXPFHBOWBEBKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261876   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM261876(2-[9-(Cyclobutylmethyl)-9H-carbazol-3-yl]-1-(cyclo...)
Affinity DataIC50:  257nMAssay Description:Antagonist activity at human EP4R assessed as inhibition of agonist-induced cAMP production by fluorescent cAMP tracer cAMP-d2 based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM261876(2-[9-(Cyclobutylmethyl)-9H-carbazol-3-yl]-1-(cyclo...)
Affinity DataIC50:  257nMT: 2°CAssay Description:4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent