BDBM26209 (2R,6S,9S)-N-(diphenylmethyl)-9-[(2S)-2-(methylamino)propanamido]-8-oxo-7-azatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),11,13-triene-6-carboxamide::Smac mimetic, 8
SMILES CN[C@@H](C)C(=O)N[C@H]1Cc2ccccc2[C@H]2CCC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1
InChI Key InChIKey=JOHHONWRDYKZMW-PSRPIYIESA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 26209
TargetBaculoviral IAP repeat-containing protein 2 [253-363](Homo sapiens (Human))
Shanghai Institute Of Organic Chemistry
Shanghai Institute Of Organic Chemistry
Affinity DataKi: 13nM ΔG°: -10.6kcal/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3 [238-349](Homo sapiens (Human))
Shanghai Institute Of Organic Chemistry
Shanghai Institute Of Organic Chemistry
Affinity DataKi: 20nM ΔG°: -10.4kcal/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Shanghai Institute Of Organic Chemistry
Shanghai Institute Of Organic Chemistry
Affinity DataKi: 690nM ΔG°: -8.31kcal/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair