BDBM262117 US11242345, Example 17::US9708325, 17::US9708325, 18::and Example 18

SMILES CCCS(=N)(=O)c1nc(N)c2[nH]c(=O)n(Cc3cccc(c3)C(N)=O)c2n1

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262117   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM262117(US11242345, Example 17 | US9708325, 17 | US9708325...)
Affinity DataEC50:  68nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM262117(US11242345, Example 17 | US9708325, 17 | US9708325...)
Affinity DataEC50:  68nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM262117(US11242345, Example 17 | US9708325, 17 | US9708325...)
Affinity DataEC50:  47nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent